Insights on C-peptide in diabetes

C-peptide, a key biomarker for beta-cell function in diabetes, has potential understanding and managing the disease, though its application type 2 diabetes is limited by insufficient evidence. It provides insights into endogenous insulin secretion faces challenges measurement standardization. In 1 C-peptide levels reflect beta cell loss, while higher indicate risk of progression. Preserved differentiate maturity onset young (MODY) from diabetes. also associated with gestational risk. shows correlations improved outcomes but controversial associations macrovascular complications. Despite promise, standardization, interpretation, utilization issues require further research trials personalized treatments